Effects of Sterofundin and Ringer‘s Lactate on acid– base status in post–surgical and trauma patients.

Rana Pratap; Sateesh Verma; Monica Kohli; Anita Malik

Volume : VIII, Issue : VI, June - 2018

Effects of Sterofundin and Ringer‘s Lactate on acid– base status in post–surgical and trauma patients.

Rana Pratap, Sateesh Verma, Monica Kohli, Anita Malik

Abstract :

Background:To study the effect of Ringer Acetate (Sterofundin B Braun®) and Ringer’s Lactate on acid– base status and serum electrolyte in post–surgical and trauma patient.

Methods:Post–surgical and trauma patient who had hypotension at the time of admission in ICU were enrolled in this study.40 patients were randomly allocated into 2 groups.Group SF and Group RL receivedSterofundinand Ringer’s lactate respectively.To achieve systolic blood pressure > 90 mmHg and urine output > 0.5 ml/ kg/ h, repeated bolus (200 ml) followed by maintenance fluid at 1.5 ml/kg/hr. was given.Outcome measures were acid– base status, serum electrolyte.

Results:No statistically significant difference was observed in pH, bicarbonate, sodium,potassium PO₂ and PCO₂ at admission and different time periods between two groups.Baseline serum lactate level, Group SF vs. Group RL (2.80±0.41 vs. 3.08±0.72 p=0.14) was similar. Group SF had significantly lower serum lactate levels at 6h, 12h, 18h and 24h (1.97 vs. 2.76, p=0.002; 1.70 vs. 2.28, p=0.01; 1.25 vs. 2.01, p=0.001; 1.09 vs. 1.93, p=0.0001).

Conclusion:Sterofundin may be preferred volume replacement solution in post–surgical and trauma cases, as it was associated with low serum lactate levels.