Efficacy of repetitive Transcranial Magnetic Stimulation as augmentation of antidepressant treatment in Patients with Severe Depressive Disorder and it‘s comparison with Lithium

Santosh Kumar Kesharwani; K. K. Verma; Harful Singh; Girish Chandra Baniya; Vineet Kumar Singh

Volume : IX, Issue : IX, September - 2019

Efficacy of repetitive Transcranial Magnetic Stimulation as augmentation of antidepressant treatment in Patients with Severe Depressive Disorder and it‘s comparison with Lithium

Santosh Kumar Kesharwani, K. K. Verma, Harful Singh, Girish Chandra Baniya, Vineet Kumar Singh

Abstract :

Depression is a state of low mood and aversion to activity that can affect a person‘s thoughts, behaviour, feelings and sense of well–being. Aims of the present study are to evaluate the efficacy of rTMS as an augmentation therapy in patients with severe depressive disorder who were nonresponsive or partial responsive to antidepressant treatment, To assess the tolerability and adverse effect profile of rTMS treatment, and To compare the efficacy of rTMS and Lithium as augmentation agent for the treatment of these patients.The study was carried out on 20 patients, who were divided in two groups (rTMS group and Lithium group), and both the groups were assessed at baseline, at 2 weeks and 4 weeks interval. It was found that rTMS augmentation is more efficacious in severe depressive disorder patients who had nonresponsive or partial responsive to antidepressant treatment than lithium augmentation and also better in side effect profile.