Efficient Method for Synthesis of 5–((benzylidene amino)methyl)–4–(substituted  phenyl),6–methyl, 3,4–dihydropyrimidin–2(1H)–ones

Rohinee R. Dharamkar; Dr. Y.K. Meshram

Volume : VII, Issue : VII, July - 2017

Efficient Method for Synthesis of 5–((benzylidene amino)methyl)–4–(substituted phenyl),6–methyl, 3,4–dihydropyrimidin–2(1H)–ones

Rohinee R. Dharamkar, Dr. Y. K. Meshram

Abstract :

A Simple and Economic Synthesis of 5–((benzylidene amino)methyl)–4–(substituted phenyl)–6–methyl, 3,4–dihydropyrimidin–2(1H)–ones by using 5–(aminomethyl)–4–(substituted phenyl)– 6–methyl– 3,4–dihydropyrimidin–2(1H)–ones and benzaldehyde in presence of ethanol. When banzaldehyde is react with primary amine i.e. 5–(aminomethyl)–4–(substituted phenyl)– 6–methyl– 3,4–dihydropyrimidin–2(1H)–ones in presence of alcoholic medium it gives formation of corresponding Schiff bases.