ELEVATED LEVEL OF BETA HUMAN CHORIONIC GONADOTROPHIN (B–HCG) IN THE SERUM OF A PATIENT WITH NON–HODGKIN‘S LYMPHOMA: A CASE REPORT AND REVIEW OF LITEREATURE

AI LADU; AM ABBA; AA BUKAR; FA ABULFATHI; Y KUNDILI; HA TALBA; Y ABBA KAWU; RA TUKUR; Y MUHAMMAD

Volume : VIII, Issue : VIII, August - 2018

ELEVATED LEVEL OF BETA HUMAN CHORIONIC GONADOTROPHIN (B–HCG) IN THE SERUM OF A PATIENT WITH NON–HODGKIN‘S LYMPHOMA: A CASE REPORT AND REVIEW OF LITEREATURE

Ai Ladu, Am Abba, Aa Bukar, Fa Abulfathi, Y Kundili, Ha Talba, Y Abba Kawu, Ra Tukur, Y Muhammad

Abstract :

Background: Reports about raise level of beta human chorionic gonadotrophin (β–hCG) is rare in the non–Hodgkins lymphoma (NHL), with few reports of elevated level in both men and post–menopausal women with NHL. We report a case of a young woman diagnosed with high grade NHL presenting with elevated level of β–hCG. Case report: The patient was a 16–year–old nulliparous woman who presented with cervical lymphadenopathy and multiple abdominal masses of varying sizes, involving the spleen, ovaries and peritoneal cavity. The serum and urinary HCG test was positive. Cytology of the splenic, ovarian masses and biopsy of the node were consistent with a high grade Non–Hodgkin lymphoma. She received two cycles of chemotherapy using CHOP regimen. Her peripheral lymphadenopathy resolved after two courses of chemotherapy and the β–hCG became negative; however, abdomino–pelvic USS showed only minimal change in the spleen size and intra–abdominal masses. She defaulted follow up thereafter, due to financial constrain. Conclusion: raised level of b HCG is rare in NHL and often associated with the high grade forms.