Volume : VII, Issue : VI, June - 2017

Emerging pattern of antibiotic sensitivity at referral neonatal intensive care center

Budensab A H, S. N. Joshi

Abstract :

 Objectives: to identify common organisms and pattern of antibiotic sensitivity among culture proven neonatal infections Methods: babies admitted to NICU with culture proven sepsis between gestational age 28 wks and above are included over 6 months period. Babies with major malformations and those undergoing surgery were excluded from the study Results: A total of 157 positive out of 452 cases. Most common bacteria was coagulase negative staphylococcus aureus (CONS) 21% followed by acetanobacter species12%, klebsiella pneumonia11% E coli8.2% entrococci8.2% pseudomonas auriginosa 6.3% Staph aureus 4.4% streptococci 2% and enterobacter1.3% and candida species 24%. CONS was sensitive to daptomycin doxycycline rifamycin levofloxacin tegicycline linezolid and vancomycin and gram negative bacteria sensitive to imipenum meropenum colistin amikacin ciprofloxacin and tegicycline. Enterococci chloramphenicol clindamycin ofloxacin erythromycin linazolid vancomycin and Staphylococcus aureus was sensitive to doxycycline daptomycin linezolid vancomycin and one MRSA sensitive to linezolid and vancomycin Candida species all sensitive to flucanazole flucytosine amphotericin B micafungin caspofungin and voricanazole with no resistance Antibiotic resistance noted to ampicillin penicillin gentamycin cefotaxime ceftrioxone and partial resistance to imipenam, meropenam Conclusions: There is an increasing trend of antibiotic resistance to the commonly used first line drugs. Continuous surveillance for antibiotic susceptibility is needed to ensure proper empirical therapy.

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Budensab A H, S.N. Joshi, Emerging pattern of antibiotic sensitivity at referral neonatal intensive care center, INDIAN JOURNAL OF APPLIED RESEARCH : Volume‾7 | Issue‾6 | June‾2017

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