Endometrial histopathological changes in cases of dysfunctional uterine bleeding at a tertiary care centre in eastern U.P.

Dr.Vatsala Kishore; Dr.Neeraj Kumar Singh; Dr.Dhananjay Kotasthane

Volume : IX, Issue : I, January - 2019

Endometrial histopathological changes in cases of dysfunctional uterine bleeding at a tertiary care centre in eastern U.P.

Dr. Vatsala Kishore, Dr. Neeraj Kumar Singh, Dr. Dhananjay Kotasthane

Abstract :

Background–DUB(Dysfunctional uterine bleeding)refers to an abnormal bleeding from the uterus,which is not caused due to tumors,inflammation,pregnancy or other organic causes.The histopathological diagnosis of DUB is very essential,especially in perimenopausal and postmenopausal females. Objective–The aim of this study was to evaluate DUB in various age groups,to study the histopathological patterns and their association with age and parity. Methods–This study was conducted at Heritage institute of medical sciences,varanasi in the department of Pathology,from january 2017 to december 2017 and 50 cases were included based on clinical features and detailed investigations.Endometrial tissue samples received either as D&C or hysterectomy specimens were included in our study and analysed for Histopathological evaluation by pathologists. Results –DUB was found to be more among women of reproductive age groups followed by perimenopausal and menipausal age.Menorrhagia was the most common type of bleeding pattern.The most common histopathological pattern was proloferative endometrium among multiparous women(2–4 children) and simple hyperplasia without atypia among the grand multiparous females. Conclusion –The cases of DUB is strongly related to patient’s age,type of menstrual cycles,menopausal status and parity.It is important to know the histopathological pattern of endometrium in patients diagnosed with atypical uterine bleeding in different age groups since the recognition of these conditions help in early and clear diagnosis and in avoiding further complications.