ETIOLOGICAL AGENTS AND THEIR SUSCEPTIBILITY TO VARIOUS DRUGS IN CASES OF ENDOPHTHALMITIS

Dr. Shrikant Thapak; Dr. Vivek Singh; Dr. P.K.Chhhawania; Dr.Anu Litoriya

Volume : VIII, Issue : VII, July - 2018

ETIOLOGICAL AGENTS AND THEIR SUSCEPTIBILITY TO VARIOUS DRUGS IN CASES OF ENDOPHTHALMITIS

Dr. Shrikant Thapak, Dr. Vivek Singh, Dr. P. K. Chhhawania, Dr. Anu Litoriya

Abstract :

PURPOSE:To find out the various bacteriological agents responsible for endophthalmitis and determine their susceptibility to antibiotics in the patients of a tertiary healthcare centre inGwalior.METHODS:Fifty cases of endophthalmitis were studied at a tertiary healthcare centre in Gwalior. Relevant clinical history was obtained. Vitreous tap were obtained and was send for microbiological evaluation to determine the etiologic agent and antibiotic sensitivity.RESULT: Positive growth was found in 74% of cases. Seven different types of bacteria were isolated. Gram–positive (86.38%) bacteria were isolated > Gram–negative (13.62%) bacteria. Single growth (70.45%) > mixed growth (29.54%). Coagulase negative staphylococci epidermidis (34.09%) were most commonly isolated, followed by staphylococcal aureus (20.45%), streptococcus pneumonia (18.18%), streptococcus pyogenes (6.81%), streptococcus viridians (6.81%), E.coli (6.81%), Hemophilus influenza (6.81%).In the present study out of 38 Gram–positive isolates vancomycin is the most sensitive drug (100%), followed by Gentmycin (94.73%), ciprofloxacin and ofloxacin (86.84%), cephalexin (84.21%), cephazoline (73.68%), chloramphenicol (65.78%). Toamycin was the least sensitive (52.63%).CONCLUSION:The most common bacterial isolate prevailing in the patients of endophthalmitis in this geographical area was Staphylococcus Epidermidis (Gram–positive, coagulase negative).During study about antibiotic susceptibility, most of the Gram positive isolates were sensitive to antibiotic Vancomycin and the Gram–negative isolates were sensitive to antibiotic Ceftazidime and Amikacin