Evaluation of Breast Cancer Metastasis to The  Skeletal System by Using Bone Scintigraphy

Mohammed A. Ali Omer; M. E. M. Gar–alnabi; Mohamed Yousef; Gada A.E. Sakin

Volume : IV, Issue : III, March - 2014

Evaluation of Breast Cancer Metastasis to The Skeletal System by Using Bone Scintigraphy

Mohammed A. Ali Omer, M. E. M. Gar Alnabi, Mohamed Yousef, Gada A. E. Sakin

Abstract :

The aim of this study was to evaluate the east cancer metastasis to specific preference parts of skeletal system using bones scintigraphy with consideration to metastatic from both easts. The sample consists of 430 patients who refereed for bone scintigraphy at radiation and isotopes center in Khartoum during 2010–2013, after a confirmation of east cancer based on histology, more variables as gender, age, involved quadrant and east, anatomical sites of metastasis from both east have been collected and analyzed. The analysis reveals that the left east was highly involved by cancer 64% relative to right one. Breast cancer starts on age group of 20–30 years old and taking the plateau at 40–50 years old then decreases following aging. The right and left easts cancer commonly gives metastases to lumbar verteae (26.7%, 22%), then dorsal verteae (14%, 19%), the pelvic bone (10%, 12.7%), the ribs (5%, 11.3%), the cervical verteae (8.7%, 10.7%), the skull (7.3%, ) and the femur bone with percentage of (6.7%, 10%) respectively and the right east cancer gives higher metastatic percent to skeletal system segments 58.1% (250) than the left east cancer41.9% (180), the predominant type of histopathology was Invasive ductal carcinoma (IDC) that representing 38% then the Adenoid carcinoma 27% and invasive lobular carcinoma 17%. The common involved quadrant by cancer was the upper outer quadrant UOQ 44%, inner upper quadrant 17%., lower outer quadrant LOQ, lower inner quadrant LIQ and the nipple showed the following percentages 17%, 15%, 13%, and 11% respectively.