EVALUATION OF CLONIDINE AS ADJUVANT WITH CAUDAL LEVOBUPIVAINE FOR POST-OPERATIVE ANALGESIA IN PAEDIATRIC AGE GROUP

Volume : VIII, Issue : IV, April - 2018

Dr. E. Lokeswara Reddy . E, Dr. Madhu Priya. V

Background: A prospective, randomized, double–blind study was designed to evaluate the effects of caudal

levobupivacaine vs. clonidine as adjuvant in children undergoing minor surgical procedures.

Methods: Sixty children of 2–8 years of age with ASA–I physical status posted for minor surgical procedures were divided in to two groups.

Group L received 0.25% levobupivacaine @1 mg/kg caudally and group C received clonidine @1μg/kg along with levobupivacaine. The

patient‘s vital data and post–operative analgesia, sedation status, motor blockade were assessed every hourly by individual scores for 24 hours.

Any adverse events were also noted.

Results: The mean duration of analgesia in group C is significantly higher(16.53+4.26)than group L(4.17+1.53).the CHIPPS scores were lower

in group C than group L which is statistically significant and 4 patients in group C did not require any rescue analgesia this is also statistically

significant. There were no incidences of adycardia, hypotension, in either of the groups during study observation.

Conclusions: Clonidine as adjuvant with caudal levobupivacaine is more efficient than levobupivacaine alone in terms of post–operative

analgesia, in caudal route and it is without any adverse side effects.