Volume : VII, Issue : V, May - 2017

Evaluation of hepatoprotective activity of Cuscuta reflexa Roxb. stem on experimental animals

Mitali Das, Alaka Das

Abstract :

 Aim: To evaluate the hepatoprotective activity of alcoholic extract of Cuscuta reflexa Roxb stem against hepatotoxicity induced by paracetamol in albino rats. Materials and methods: Stems of Cuscuta reflexa were collected, air dried and powdered. Methanolic extract was obtained by percolating the dried powder with 99.8% methanol.        Oral toxicity test was done according to OECD guidelines. Hepatoprotective activity was evaluated by the method described by Lahon K and Das S. Alcoholic extracts of Cuscuta reflexa (100mg/kg) was used as test drug and Silymarin 100 mg /kg as standard drug. All medicaments were given for 10 days. Hepatotoxicity was induced by a   single dose of Paracetamol 2 gm/kg body weight on 8th day of the experiment. Results: Alcoholic extract of Cuscuta reflexa stem showed significant (p < 0.01) hepatoprotective activity when compared to the control.

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

MITALI DAS, ALAKA DAS, Evaluation of hepatoprotective activity of Cuscuta reflexa Roxb. stem on experimental animals, INDIAN JOURNAL OF APPLIED RESEARCH : Volume‾7 | Issue‾5 | May‾2017

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