Volume : VIII, Issue : VII, July - 2018

EVALUATION OF LIPID PROFILE IN CHRONIC KIDNEY DISEASE

Manpreet Saini, Nita Garg

Abstract :

Aim:The aim of our study was to estimate the levels of Serum T.Cholestrol, HDL, LDL, TG, T.Cholestrol/HDL ratio and LDL/HDL ratio to establish a correlation of them in Chronic Kidney Disease patients.

 

Study Design:A hospital based Non–Experimental Observational Cross–sectional & Correlation Study was conducted on patients of both sex attending the Out Patient Department& In Patient Department of Nephrology & Medicine of SMI Hospital, P.Nagar Dehradun for a period of 4 months from January 2014 to April 2014. Study comprises 54 patients with evidence ofChronic kidney diseaseselected randomly of both sex & age above 15 years as Test Group & 50 healthy individuals sourced from hospital staff/ students & patients relatives as Control Group.Exclusion criteria was age ≤15 years & those not willing to participate.

 

Methdology:Consecutive sampling technique &Bio–physiological method of collection of Data was used .5ml blood was collected in sterile tubes from the fasting (8–12hrs) test group & control group and was analyzed for Serum T.Cholestrol, HDL,LDL, TG, T.Cholestrol/HDL ratio &LDL/HDL ratio by enzymatic method using VITROS ECIQ,an auto analyser at SMI Hospital,P.Nagar, Dehradun.

 

Results:Serum VLDL levels &T.Chol/HDL ratio levels were found to be Nonsignificantly (P>0.05) elevated inChronic kidney disease patients as compared to control group, while serum Cholesterol, HDL, LDL levels were non significantly lower (P>0.05) in Chronic kidney disease patients. Serum LDL/HDL ratio levels were significantly (P<0.05) lower. Serum TG levels were highly significantly (P<0.01) elevated in Chronic kidney disease patients when compared to control group.

Statistically there was non significant elevation(P>0.05)of Serum T.Cholesterol, LDL,HDL, VLDL, T.Cholesterol/HDL & LDL/HDL ratio levels in female Chronic kidney disease Group as compared to male Chronic kidney disease group. Serum TG levels were found to be non significantly lower (P>0.05) in female Chronic kidney disease Group as compared to male Chronic kidney disease Group.

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Manpreet Saini, Nita Garg, EVALUATION OF LIPID PROFILE IN CHRONIC KIDNEY DISEASE, INDIAN JOURNAL OF APPLIED RESEARCH : Volume-8 | Issue-7 | July-2018


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