EVALUATION OF LV FUNCTION BY 2 D STRAIN ECHO BEFORE AND AFTER THROMBOLYSIS.

Dr.P.Prabhakar; Dr.S.SathishKumar; Dr.S.Balasubramanian; Dr.S.R.Veeramani; Dr.S.Naina Mohammad; Dr.G.S.Sivakumar; Dr.R.Ramesh; Dr.T.R.Hemanath; Dr.G.Selvarani; Dr.Nagasundar; Dr.Saravanan

Volume : VIII, Issue : VII, July - 2018

EVALUATION OF LV FUNCTION BY 2 D STRAIN ECHO BEFORE AND AFTER THROMBOLYSIS.

Dr. P. Prabhakar, Dr. S. Sathishkumar, Dr. S. Balasubramanian, Dr. S. R. Veeramani, Dr. S. Naina Mohammad, Dr. G. S. Sivakumar, Dr. R. Ramesh, Dr. T. R. Hemanath, Dr. G. Selvarani, Dr. Nagasundar, Dr. Saravanan

Abstract :

Objectives:

To assess longitudinal strain of individual segments and global LV systolic function usingnovel parameter 2D speckle tracking by automated functional imaging (AFI)inpatients with acute ST–elevation myocardial infarction before and after thrombolysis and to compare them with traditional parameters like wall motion score index(WMSI) and left ventricular ejection fraction(LVEF)

Methods

This was a single centre, prospective observational study conducted in the cardiology department of Madurai government Rajaji hospital from march 2017 to may 2018.Patients who presented with features of acute ST elevation myocardial infarction (STEMI) thrombolysedwith inj. streptokinase were enrolled in the study. All patients were submitted to 2D TTE to assess the longitudinal strain of individual segments and global LV function by novel parameter 2D speckle tracking by automated functional imaging (AFI).

Results:

In our study, 50 cases of acute ST–elevation myocardial infarction , each 25 cases from AWMI and IWMI , thrombolysed with streptokinase were taken up for our study.

Among AWMI and IWMI patients, WMSI was reduced in post thrombolytic state. Whereas GLS and LVEF, both showed improvement after thrombolysis. Also there was a positive and linear correlation between these parameters, pre and post thrombolysis.

Conclusion:

Our study has shown that in acute ST elevation MI , global longitudinal strain(GLS) by STE is more sensitive than LVEFand non–inferior to WMSI as a marker of LV dysfunction.