Evaluation of status of serum uric acid and lipid profile in Essential Hypertension

Volume : VIII, Issue : I, January - 2018

Dr. Smita Padhy, Dr. Himanshu Sekhar Dash

Uric acid is a byproduct of purine metabolism,has been recently considered as a

risk factor for hypertension,metabolic syndrome,cardiovascular

disease.Hypertension and dyslipidemia are major risk factors for cardiovascular

disease.The present study was undertaken to evaluate the association of uric acid

and lipid profile with hypertension.The study was conducted by taking 50

hypertensive patients and 50 healthy subjects.The uric acid and lipid profile were

measured in both the groups.It was revealed that mean serum uric acid was

significantly increased in hypertensive patients as compared to controls. Mean

serum total–cholesterol,LDL–cholesterol,VLDL–cholesterol and triglycerides were

significantly increased in cases as compared to controls.Mean serum HDL–

cholesterol was significantly decreased in cases as compared to controls.

The study shows that both serum uric acid and lipid profile are associated with

hypertension.Therefore hypertensive patients should undergo regular

measurement of both these parameters to prevent cardiovascular disease.