EVALUATION OF THROMBOCYTOPENIA IN A TERTIARY CARE CENTRE

DR. K.F. MAGDALENE

Volume : VI, Issue : I, January - 2016

EVALUATION OF THROMBOCYTOPENIA IN A TERTIARY CARE CENTRE

Dr. K. F. Magdalene

Abstract :

Background– Thrombocytopenia is one of the most common cause of abnormal bleeding . Objective–To establish a pattern of differential diagnosis of thrombocytopenia Material and method– 200 cases of thrombocytopenia reported on peripheral blood smear during 2 year period (October 2013– September 2015) were studied. RESULT– 55 cases (27.5%) of thrombocytopenia were due to Idiopathic thrombocytopenic purpura. Infections (42cases, 21%), hematological malignancies(21 cases,10.5%), megaloblastic anemia(19cases, 9.5 %), aplastic anemia(16 cases, 8 %), hypersplenism (12cases, 6%), drugs (12 cases, 6%), Alcoholism ( 6cases, 3%), immunologic disorders ( 3cases,1.5 %), Paroxysmal nocturnal hemoglobinuria (3 cases,1.5%), Valvular heart diseases (3 cases,1.5 %), Pregnancy (2 cases,1 %) and other disorders (3%) caused thrombocytopenia. CONCLUSION– The incidence and causes of thrombocytopenia may vary, depending on age group, geography, health care setup where the study is conducted and method used for diagnosing thrombocytopenia .