Volume : VIII, Issue : VI, June - 2018

Evaluation of Thyroid dysfunction in chronic kidney disease

Manpreet Saini, Nita Garg

Abstract :

Aim:The aim of our study was to estimate the levels of Serum T3, Serum T4 and Serum TSH to establish a correlation of these hormones in CKD patients.

 

Study Design: A hospital based cross sectional study was conducted on patients (both male & female) attending the Out PatientDepartment of Nephrology & Medicine and those admitted in SMI Hospital for a period of 4 months from January 2014 to April 2014. 54 cases (both male and female) above 15 years of age were selected randomly for the study. A control group of 50 subjects comprising of Medical staff/ students who had no signs & symptoms of Renal disease were included in the study.

Exclusion criteria was age less than 15 years and those not willing to participate.

 

Methodology: 5ml blood was collected in sterile tubes from all the 104 subjects and was analyzed for serum T3, serum T4 and Serum TSH on a fully automated Biochemical Analyzer of Orthoclinical Diagnostics 5600.

 

Results:Serum T3 levels were found to be significantly low (p<0.01) in CKD Patients as compared to the control groups. Serum T4 levels are significantly low (p<0.05) and serum TSH is significantly elevated (p<0.01) in CKD patients when compared with control group.

The statistical analysis demonstrated that there is a nonsignificant (p>0.05) elevation of serum T4 levels in CKD female group when compared to male CKD group. Serum T3 and Serum TSH were nonsignificantly (p>0.05) lower in CKD female group than CKD male group.

Keywords :

Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Manpreet Saini, Nita Garg, Evaluation of Thyroid dysfunction in chronic kidney disease, INDIAN JOURNAL OF APPLIED RESEARCH : Volume-8 | Issue-6 | June-2018

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