Volume : VIII, Issue : I, January - 2018

Ewing‘s Sarcoma: A Review Article

Dr. V. Hemavathy, Jeeva Jose

Abstract :

 

Ewing sarcoma is the second most common bone cancer in children. It occurs most frequently in the long bones of the legs or arms, the pelvis, chest wall, spine and the skull, but can also begin in the soft tissues and not involve bone. This disease most often occurs in adolescents, with nearly half of cases arising between the ages of 10 and 20. Ewing sarcoma is somewhat more common in males than in females. The Ewing Family of Tumour” includes Ewing sarcoma, atypical Ewing sarcoma, and peripheral primitive neuroectodermal (PNET) of bone or soft tissue, and they are all treated in the same manner. A chromosomal mutation can be identified in the tumour cells of the Ewing Family of Tumour. The chromosomal mutation is not part of the genetic make–up of the person with the tumour, it is only in the tumour cells; the tumour is not inherited. The cause of the Ewing Family of Tumour is not yet known but it is believed this mutation plays an important role. Chemotherapy with alternating courses of 2 regimens: vincristine, doxorubicin, and cyclophosphamide; and ifosfamide and etoposide, Neutrophil support, Red blood cell and platelet support, Surgery and/or radiotherapy.

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Dr. V. Hemavathy, Jeeva Jose, Ewing's Sarcoma: A Review Article, INDIAN JOURNAL OF APPLIED RESEARCH : Volume-8 | Issue-1 | January-2018


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