Volume : IX, Issue : IX, September - 2019

Ferric Carboxy Maltose In Anaemia In Pregnancy

Dr Lalit D. Kapadia, Dr Juhi R. Mehta

Abstract :

BACKGROUND: Iron deficiency is the common nutritional deficiency amongst women of child beå age. Peripartum iron deficiency anaemia is associated with significant maternal, fetal and infant morbidity. Current options include oral iron supplementation, which can be ineffective and poorly tolerated, parenteral iron preparations and red blood cell transfusions, which carry an inherent risk and should be avoided. Ferric carboxy maltose is a new treatment option that may be better tolerated. The study was designed to assess the safety, efficacy and tolerability of intravenous ferric carboxymaltose for correction of iron deficiency anaemia in antenatal or postnatal period. METHOD: Prospective cohort study, 50 iron deficiency anaemic antenatal or postnatal women received ferric carboxy maltose. Anaemia was diagnosed based on Hb levels and iron deficiency was diagnosed based on serum ferritin levels(<30µg/l). Administration of FCM (15 mg/kg, maximum of 1000 mg) over 15 minutes was well tolerated. Treatment effectiveness was assessed by follow up hemoglobin levels after 3 weeks. Safety and tolerability was assessed by analysis of adverse drug reactions and fetal heart rate monitoring in antenatal patients during the infusion. RESULTS: Most of the women were in the age group of 22–30 years and had moderate anaemia as per WHO guidelines. Intravenous ferric carboxy maltose infusion significantly increased mean Hb values above baseline levels in almost all women. Increased Hb values were observed at 3–8 weeks post infusion. No serious adverse effects were found. CONCLUSIONS: Intravenous ferric carboxymaltose was safe and effective in antenatal and postnatal patients with iron deficiency anaemia. It elevates Hb level and restores iron stores faster than other IV iron injectables and oral iron.

Keywords :

Article: Download PDF    DOI : 10.36106/ijar  

Cite This Article:

FERRIC CARBOXY MALTOSE IN ANAEMIA IN PREGNANCY, Dr Lalit D. Kapadia, Dr Juhi R. Mehta INDIAN JOURNAL OF APPLIED RESEARCH : Volume-9 | Issue-9 | September-2019

Number of Downloads : 214

References :