Volume : VII, Issue : I, January - 2017

FETAL NUCHAL TRANSLUCENCY BY ULTRASOUND A SCREENING TOOL FOR FETAL ABNORMALITIES

Dr. M. Meena, Dr. D. Narmadha

Abstract :

 To assess fetal nuchal translucency in an unselected population of  pregnant  women  with  viable  singleton pregnancy  and  usefulness  of  increased  Nuchal  translucency in  identifying  abnormal  fetuses.

 

SUBJECTS & METHODS :–

            A Prospective study consisting  of 100 antenatal  women was  conducted  in  kasturba Gandhi hospital, Chennai, after obtaining ethical clearance from IEC , madras medical college. Women with NT >95th percentile for that gestational  age  and CRL, were considered to be at high risk (screen positive).For screen positive women, fetal karyotyping  was done  after counseling  them regarding the risk  for  having an anomalous fetus. Chi–square test  and student t test  were used  to  find  the statistical significance in the noted difference  of anomalies associated with  the fetuses  with  increased  NT using  statistical  software namely SPSS version 15.A  sample  size  of 100  was  arrived  using G power  3.0.10  software  which  determines  the significance size  at  0.01  and  power of 0.99.

RESULTS :–

            The  mean  age  for  women  with  normal  NT : 24.4 years (SD–4.4),  mean age for women with abnormal NT : 28.8 years(SD –6.5).All  fetuses  with  increased  NT had abnormal outcome showing that  NT  is  an effective  method  of screening  for fetal abnormalities. statistically  significant difference  seen  in  the  incidence  of  increased  NT  among antenatal   women  who were  older  than  30 years  and  the  P value  <0.01. The  diagnostic  value  of  increased NT  in relation to  cardiac  defects  sensitivity  is 100%,  specificity  is  96.9%, positive  predictive  value  is  40%  and  the  p value  is < 0.001. Increased  NT was  significantly  associated  with  abnormal fetuses was statistically  significant  p<0.001  and  with syndromic   fetus  p value <0.001.

 

CONCLUSION:–

            Our study confirms that all fetuses with increased NT had adverse  pregnancy outcome. 40% had chromosomal anomalies .Isolated cardiac  defects were identified among 40% fetuses,20% had spontaneous miscarriage. Incidence of increased NT is higher in women more than 30 years (28.6%), against women less than 30 years (3.1%), indicating higher risk for fetal abnormalities in the former group. 

Keywords :

Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

DR.M.MEENA, DR.D.NARMADHA, FETAL NUCHAL TRANSLUCENCY BY ULTRASOUND A SCREENING TOOL FOR FETAL ABNORMALITIES, Indian Journal of Applied Research,Volume : 7 | Issue : 1 | JANUARY 2017


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