Gall Bladder Motility Study Evaluation of  Asymptomatic Gall Bladder Stones

Ashish Verma; S K Bhartiya; S P Basu; R C Shukla; V K Shukla

Volume : III, Issue : X, October - 2013

Gall Bladder Motility Study Evaluation of Asymptomatic Gall Bladder Stones

Ashish Verma, S K Bhartiya, S P Basu, R C Shukla, V K Shukla

Abstract :

Aim: To evaluate the validity of gall bladder motility study as a surrogate of GB functional abnormality in patients with incidental asymptomatic gall bladder stone. Asymptomatic cholelithiasis raise significant concern and it is vital to evaluate evidences for elective surgical management. Further, the evidences from existing body of literature are correlated with findings of this study to suggest a possible role of this useful technique. Methods: Gall bladder motility study was carried out by ultrasound screening after ingestion of test meal in 54 consecutive cases of asymptomatic gall bladder diseases and in 18 healthy volunteers in our tertiary care center based in a busy university hospital. Results: 61.1% of cases were poor contractors as compared to 11.1% of controls. The fasting volume of GB in cases, was significantly higher (p < 0.04) than in controls. The PP1,PP2 and PP3 were significantly higher in cases of good contractors group as compared to the controls, the volumes being also higher in cases of poor contractors group. The EV was significantly low in poor contractors with a consequent significantly higher RF than the good contractors. The residual fraction was significantly higher in cases as compared to controls (p<0.02) Conclusion: Gall bladder motility study metrics are viable imaging markers for GB functional compromise. The variables evaluated hitherto are independent predictors of GB function. Evidences from contemporary and historically important literature, point towards a direct role of gall bladder stone in causation of complications. It is therefore hypothesized, that elective surgery based on patient selection in accordance with the parameters calculated hereby, can lead to a statistically significant reduction in complication caused by an asymptomatic gall stones. RUNNING TITLE Early detection of asymptomatic gall bladder stones can lead to a reduction in complications of calculus cholecystitis. / prediction / potential for formation of stones by gall bladder motility studies