Volume : V, Issue : IV, April - 2015

Helicobacter pylori infection: susceptibilty to antimicrobials and eradication rate in pluritreated pangastritis patients

Mascellino, M. T. , Oliva, A. , M. De Angelis, Porowska B.

Abstract :

 Aim of our study was to evaluate the utility of the culture and the subsequent susceptibility testing in a 

group of 100 pluritreated patients with pangastritis undergone several therapy cycles.
Out of 100 patients, culture and susceptibility testing was obtained in 62 patients (62%) whereas in 38 (38%) no H. pylori growth was detected. The culture–positive group was treated following the antibiogram results whereas the culturenegative group was empirically treated. In the first group, the eradication rate was 77% (48/62) whereas in the second 
group, 32/38 subjects (84%) were eradicated with empirical or standard therapy. 
The eradication rate of the patients with antrum prevalent pangastritis was higher than in the patients with corpusfundus or diffuse pangastritis (96%, 75% and 61% respectively).The difference between the two groups (77% and 84% 
respectively; p=0.72), even if not statistically significant demonstrates that a successful eradication can be achieved 
even without antibiogram.

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Mascellino, M.T., Oliva, A., Glocker E, Porowska B. Helicobacter pylori infection: susceptibilty to antimicrobials and eradication rate in pluritreated pangastritis patients Indian Journal of Applied Research, Vol.5, Issue : 4 April 2015


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