HEPATITIS E ASSOCIATED AUTOIMMUNE HEMOLYTIC ANEMIA�A RARE CASE PRESENTATION

Sheenam Sood; Mahadeo Mane; Veer Thakkar

Volume : VI, Issue : VI, June - 2016

HEPATITIS E ASSOCIATED AUTOIMMUNE HEMOLYTIC ANEMIA�A RARE CASE PRESENTATION

Sheenam Sood, Mahadeo Mane, Veer Thakkar

Abstract :

 Autoimmune haemolytic anemia (AIHA) is a rare disease characterised by hemolysis, requiring varying degrees of blood transfusions. Autoantibodies are directed against red blood cells which cause their premature destruction by macrophages from the reticuloendothelial system leading to anemia. Warm antibody type autoimmune haemolytic anemia is the most common AIHA. Secondary autoimmune haemolytic anemia due to various viral infections has been documented. Hepatitis viruses A, B and C have been commonly implicated in causing AIHA. Hepatitis E virus (HEV) causing AIHA is rare. We present a case of AIHA, in which the patient tested positive for HEV IgM antibodies, demonstrating association of acute HEV infection with AIHA.