Volume : IV, Issue : III, March - 2014

Histological and Biochemical Alterations in Liver of Rattus Rattus Trapped From Vegetable Fields

S. S. Hundal, Anuja Gupta

Abstract :

Pesticide toxicity has gained considerable attention in the recent years leading to a postulation that they are a major cause of environmental deterioration. A number of pesticides are sprayed on vegetable crops and field rats are continuously being exposed to the mixed concentration of pesticides. The present study was designed to assess the histological and biochemical alterations in liver of the female rats due to pesticide exposure trapped from the vegetable fields. Enzyme assays have showed a significant increase (P≤0.05) in alanine transferases (ALT), asparate transferases (AST), acid phosphatase (ACP), alkaline phosphatase (AKP), total lipids, phospholipids and cholesterol in liver homogenate which may be due to pesticidal stress. Total proteins in liver showed a non significant (P≥0.05) increase. Histological alterations (vacuolization, nuclear fragmentation, infilteration, pyknosis and sinusoidal dilations) have been observed and indicated that pesticides have caused a serious damage to the organ.

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

S.S. Hundal, Anuja Gupta Histological and Biochemical Alterations in Liver of Rattus Rattus Trapped From Vegetable Fields Indian Journal of Applied Research, Vol.IV, Issue. III

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