Histomorphological study of premalignant and malignant lesions of skin.

Dr. Fouzaan Shekhani; Dr. Sudhamani. S; Dr. Manthan Patel; Dr. Prakash Roplekar

Volume : VI, Issue : VI, June - 2016

Histomorphological study of premalignant and malignant lesions of skin.

Dr. Fouzaan Shekhani, Dr. Sudhamani. S, Dr. Manthan Patel, Dr. Prakash Roplekar

Abstract :

 Background: Histopathology remains the gold standard for the diagnosis of skin tumors. There is limited data on the distribution and occurrence of these skin tumors in literature. In addition, premalignant tumors of skin are commonly seen on sun–exposed areas, especially in tropical countries like India. It is important to recognize these distinctive entities based on that clinical data with histomorphological features and guide the dermatologists for treatment and prognostication. The present study aims to study the premalignant and malignant tumors of skin in a tertiary care teaching hospital and to categorize them according to their histopathological features. Aims and Objectives: 1. To study the various clinico–histopathological features including age, sex, site distribution skin tumors. 2. To find the frequency of benign, malignant and premalignant tumors of the skin. Materials and Methods: Skin biopsies and surgically resected specimens of skin tumors done for diagnostic and therapeutic purposes were studied. They were then categorized based on their clinical and histopathological features. Result: A total of 51 patients were studied with clinic–pathological correlation. Most of the tumors were benign followed by malignant and premalignant condition. Majority of skin tumors were seen in the age–group of 51–60 years followed by 11–20 years with the head and neck area being the most common site. The most common type of skin tumor was found to be keratinocytic (52.9%) with the squamous cell carcinoma as the most common tumor. Conclusion: Squamous cell carcinoma is the most common skin tumor of skin mainly seen on sun exposed areas. Histopathology plays a major role in identifying the varied features of premalignant and adnexal tumors of skin.