Histopathological analysis of gallbladder lesions in a tertiary care hospital in Andhra pradesh

Kasa Lakshmi; Lavanya sangati; V.Jyothi; D. Anitha Rani

Volume : VII, Issue : XI, November - 2017

Histopathological analysis of gallbladder lesions in a tertiary care hospital in Andhra pradesh

Kasa Lakshmi, Lavanya Sangati, V. Jyothi, D. Anitha Rani

Abstract :

Introduction : This study is done to report the frequency of gall bladder lesions and histopathology of various lesions of 315 cholecystectomies from January 2015 to January 2017. Gall bladder may be affected by infection, inflammation, benign and malignant conditions. Among all gall stones are the commonest biliary pathology.

Aim : To study the histopathological spectrum of lesions of gall bladder.

Meterials and methods: A retrospective study was carried out over a two years period from January 2015 to January 2017. A total of 315 gall bladder specimens were received in the department of pathology. Clinical details and histoplogical findings were analysed to determine the incidence and prevalence of various gall bladder lesions.

Results: There were 315 cholecystectomy specimens. Male to female ratio was 1: 1.7. Majority of the patients were between 41 – 50 years. Chronic cholecystitis was the commonest condition seen in232(73.65%) . Other benign diseases were acute cholecystitis58(18.41%), Xanthogranulomatous cholecystitis 3(0.95%), gallbladder polyps 7 (2.22% ), cholesterosis 6(1.9%) and acute gangrenous cholecystitis 5(1.58%). Four cases ( 1.26% ) showed adenocarcinoma.

Conclusion: Chronic cholecystitis is the commonest lesion of gallbladder with female predominance and most of them are associated with gall stones. Routine histopathology of all cholecystectomy specimens is needed as subsequent report would provide evidence of malignancy which helps in further management of the patient and better prognosis.