Volume : III, Issue : VII, July - 2014

Histopathological Changes in Liver Tissue of Heteropneustes Fossilis Exposed Chlorpyrifos (20% Ec)

Hasina Begum Barbhuiya, Dr. Mithra Dey

Abstract :

The acute toxicity of Chlorpyrifos to Heteropneustes fossilis was assessed for 96 hrs. LC50 value was computed using probit method and found to be 1.2 µl/L. During acute toxicity test fish showed several behavioural changes like– gulping of air at water surface, swimming at the water surface, hanging vertically in water, increased mucus secretion and staying motionless at the bottom of the test chamber. For chronic study a sub lethal concentration of 0.12 µl/L (1/10th of LC50) was choosen and histopathological changes in the liver was studied. The liver of treated fish showed congestion of central vein, degeneration of hepatocytes, cytoplasmic vacuolization, hepatocytes with pyknotic nuclei, and thrombosis in hepatoportal blood vessel. Haemorrhage around the central vein, necrosis and haemosiderin was also observed. These findings present the negative impact of the surrounding environment.

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Hasina Begum Barbhuiya, Dr.Mithra Dey Histopathological Changes in Liver Tissue of Heteropneustes Fossilis Exposed Chlorpyrifos (20% Ec) Indian Journal of Applied Research, Vol.4, Issue.7 July 2014

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