Volume : IX, Issue : XII, December - 2019

HISTOPATHOLOGICAL CHANGES IN PRODUCT OF CONCEPTION

Krishmitha Palani

Abstract :

INTRODUCTION : The main explanation of routine histopathologic examination of merchandise of conception is to discover associate degree extrauterine pregnancy or a abnormally, that need more management. Retained merchandise of conception (RPOC) are a typical and treatable complication when delivery or termination of maternity. The pathologic diagnosis of RPOC is made based on the presence of chorionic villi, which indicates persistent placental or trophoblastic tissue. AIM : To evaluate the histopathologic findings regarding tissue samples collected at surgical female internal reproductive organ evacuation in first–trimester spontaneous miscarriages. METHODS: In this retrospective study, histopathologic diagnosis of the tissue samples obtained via surgical uterine evacuation in patients in a 12–month period with the diagnosis of incomplete miscarriage (n = 70), missed miscarriage (n = 21) , complete miscarriage (n = 3) and blighted ovum (n = 6) in the first trimester was recorded and compared with the pre–surgery diagnosis. RESULT : Among 100 cases of spontaneous abortions, products of conception was seen in 69 (69%) and with only 2 cases of choriocarcinoma. Majority of cases belongs to cohort 21–30 years. The most common decidual changes were inflammation (39%) followed by fiin deposition 29%. Majority of the cases shows hydropic changes as histopathological changes in sac villi. In the present study, minimum age of lady was 18 years and the maximum age was 40 years . Among the cases, maximum 76 (76%) of them belonged to age group 21–30 years. Correlating the age group with number of abortions was found to be significantly different among four different age groups. CONCLUSION : By routine histopathologic assessment of product of first‐trimester spontaneous miscarriages, important pathologies like abnormality and placental tissue layer sickness are often diagnosed. Histopathological assessment has nice worth within the identification of Associate in Nursing ectopic gestation or infection in comparison with clinical and laboratory findings.

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Article: Download PDF    DOI : 10.36106/ijar  

Cite This Article:

HISTOPATHOLOGICAL CHANGES IN PRODUCT OF CONCEPTION, Krishmitha Palani INDIAN JOURNAL OF APPLIED RESEARCH : Volume-9 | Issue-12 | December-2019

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