Histopathological evaluation of routine cholecystectomy specimens with special emphasis on incidental carcinoma and dysplasia: A 3 year retrospective study in a tertiary care centre in North East India

Dr. Muktanjalee Deka; Dr. Rwishumwi Daimari; Dr. Sukrita Bhattacharjee

Volume : VIII, Issue : I, January - 2018

Histopathological evaluation of routine cholecystectomy specimens with special emphasis on incidental carcinoma and dysplasia: A 3 year retrospective study in a tertiary care centre in North East India

Dr. Muktanjalee Deka, Dr. Rwishumwi Daimari, Dr. Sukrita Bhattacharjee

Abstract :

Introduction: Cholecystectomy is one of the most common surgeries performed. This study aimed to analyse the histopathological spectrum of all gallbladder specimens with special emphasis on incidental diagnosis of dysplasia and carcinoma.

Materials and methods: Retrospective analysis was done on blocks and slides of all cholecystectomy specimens received during October 2014 to September 2017 in our institution. All known carcinoma cases were excluded.

Results: Out of 3748 cholecystectomy specimens studied, 2911(77.67%) patients were female and 837(22.33%) patients were male. Histopathological analysis showed 3701 benign cases, 11 cases of dysplasia and 36 cases of gallbladder carcinoma. Dysplasia and carcinoma cases peaked in the age group of 41–50yrs. The incidence of incidental gallbladder carcinoma in our study was 0.96%.

Conclusion: Histopathology of gallbladder helps to assess non–neoplastic and precancerous changes. In a high risk zone, all gallbladder specimens should be subjected to histopathology so that incidental carcinoma is not missed.