Histopathological findings in liver autopsies; A review of 70 cases in a tertiary care center.

Dr.Lakshmibai B Malllappa; Dr.Shayesta Jahan

Volume : VIII, Issue : VI, June - 2018

Histopathological findings in liver autopsies; A review of 70 cases in a tertiary care center.

Dr. Lakshmibai B Malllappa, Dr. Shayesta Jahan

Abstract :

Introduction : Liver is a very important organ for many diseases . They could be either primary or secondary diseases. The most common secondary involvement of liver maybe due to cardiac, metabolic and social problems like alcoholism. In addition, drug toxicity , injudicious use of topical applications, herbal remedies and environmental exposures also play a major role in the causation of liver diseases.

Aims and Objectives:

1. This study aims at finding out the prevalence of liver diseases in random autopsy specimens..

2. It also gives an idea about the various diseases involving the liver and the nature of their severity.

Materials and Methods:

This study was conducted in the Department of Pathology; Victoria hospital, Bangalore Medical College and Research Institute, Bangalore. The autopsy specimens were sent by the Department of Forensic Medicine of the same Institute. It is a randomized study choosing a month of each year between 2013 to 2017. A total of 70 cases were included in this study. Tissue sections were made and stained with Hematoxylin & Eosin stain and Masson’s Trichome stain.

Results:

The total number of cases were 70. Liver diseases were predominant in males. The number of cases in males were 59(84%) and females were 11(16%). Male to female ratio was 5:1. Mean age was 35 years. The most common age group involved was 21–30 years with 24(34.28%) cases. Followed by the age group of 31–40 years 14 cases(24.28%). 1 case (1.42%) each was noted in the age group of 71–80 years and 81–90 years respectively. The most common histopathological finding was steatosis 25(35.7%) cases, followed by congestion 19(27.14%) cases.11(15.7%) cases of Steatohepatitis, 4(5.71%) cases of Chronic Venous Congestion,3(4.28%) cases of Cirrhosis. 1 each (1.42%) of Cavernous Hemangioma, Hepatocellular carcinoma, military tuberculosis and Leukemia/lymphoma infiltration were noted. 4(5.71%) cases were unremarkable.

Conclusion:

Autopsy plays a very significant role in finding out the cause of death. It also contributes to the macro and histopathological findings and clinical information.