Volume : IX, Issue : III, March - 2019

HISTOPATHOLOGICAL SPECTRUM OF CENTRAL NERVOUS SYSTEM TUMORS

Dr. P. Venkata Kiran Kumar, Dr. J. Bhagya Lakshmi

Abstract :

Background: Central nervous system (CNS) tumors are considered as most notorious in all types of cancers. Incidence of CNS tumors in developing countries is lower as compared to developed countries, but increased rate has been observed in both. The aim of the study was to highlight the incidence and histological spectrum of CNS tumors in our region, to diagnose and classify CNS tumors according to WHO classification. Material and Methods: this retrospective histological analysis of CNS tumors was carried out in the department of pathology from July2015 to June2018. During this period, a total of 305 neurosurgical specimens were received in the department. The specimens were processed by routine histotechniques and immunohistochemistry was performed whenever required. The diagnosed CNS tumors were studied and classified according to WHO classification. Results: among 305 cases, astrocytomas (37%) were commonest followed by meningiomas (26%). Cranial and spinal nerve sheath tumors (11%) and metastatic tumors (9%) were encountered. Tumors were seen in all age groups but mean age group affected was 41–50yrs accounting for 79(26%) cases. Male to female ratio of 1:1.4 was noted with female preponderance. Conclusion: the present study helps to provide information regarding the burden of disease in our area. Despite the use of modern imaging technique that helps in provisional diagnosis of disease, histological examination is gold standard in diagnosis of varied types. Further utility of immunochemistry aids in confirmation and prognosis of disease.

Keywords :

Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

HISTOPATHOLOGICAL SPECTRUM OF CENTRAL NERVOUS SYSTEM TUMORS, Dr.P.Venkata Kiran Kumar, Dr. J. Bhagya Lakshmi INDIAN JOURNAL OF APPLIED RESEARCH : Volume-9 | Issue-3 | March-2019

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