Histopathological Spectrum Of Prostatic Lesions: A Retrospective Analysis Of Transurethral Resection Of Prostate Specimens In A Tertiary Care Hospital.

Priyanka G. Ingole; Sanjay D.Deshmukh; Sadhana H.Khaparde; B.B.Shinde; Aarti K Buge

Volume : IX, Issue : IX, September - 2019

Histopathological Spectrum Of Prostatic Lesions: A Retrospective Analysis Of Transurethral Resection Of Prostate Specimens In A Tertiary Care Hospital.

Priyanka G. Ingole, Sanjay D. Deshmukh, Sadhana H. Khaparde, B. B. Shinde, Aarti K Buge

Abstract :

Background: The incidence of prostatic lesions increases with the advancing age, prostatic cancer (PCa) is the second most common cancer among males. Diagnosis is usually done by microscopic study of transrectal core biopsy and TURP is the commonly performed surgery. Objective 1) To evaluate the spectrum of prostatic lesions as per histopathological classification of WHO .2)To highlight the rare cases. Methods: The present study included 328 cases of TURP specimens received from January 2016 to December 2018 in the Pathology. 10% neutral buffered formalin was used as fixative and sections were stained with H&E stain.. The results of present series were compared with other reported studies . Results: Out of 328 TURP specimens 150 (45.73%) were Benign Nodular Hyperplasia(BHP). 119 (35.36%) (BHP) with chronic prostatitis, 22(6.70%) were adenocarcinoma prostate. Among BHP, Basal cell hyperplasia was seen in 9(2.745%) cases. Squamous metaplasia in 3(0.91%) and Urothelial metaplasia in 1(0.30%)case. The rare lesions encountered were granulomatous prostatitis 2(0.60%) cases. Atypical Adenomatous Hyperplasia in 3(0.91%) cases. There were 14(4.26%) cases of Low grade Prostatic Intraepithelial Neoplasia(L PIN ) and 5(1.52%) cases of High grade PIN (H PIN). In the group of adenocarcinoma 1(0.30 %) case had associated malakoplakia.,there were 2 (0.60%) cases of signet ring cell type adenocarcinoma. Conclusions: BHP is the most common non neoplastic prostate lesion, most commonly encountered in age group of 61 to 70 years.