Histopathological spectrum of vesiculobullous lesions of skin: A hospital based cross sectional study

Dr. Umang Bhargava; Dr. Garima Dundy; Dr. Vishal Agrawal

Volume : VI, Issue : V, May - 2016

Histopathological spectrum of vesiculobullous lesions of skin: A hospital based cross sectional study

Dr. Umang Bhargava, Dr. Garima Dundy, Dr. Vishal Agrawal

Abstract :

Aim: A few people in North India have attempted a detailed histopathological examination of VBL. Present study was aimed to oaden the wide histopathological spectrum of VBL and be cognizant of various differential diagnoses. Settings and design: A cross–sectional, hospital based study was undertaken in the Department of Pathology, S.N. Medical College Agra during the study period of 18 months. Material and methods: A total of 45 skin biopsies clinically labeled as VBL were subjected to routine histoprocessing. Results: Clinically labeled VBL constituted 18.36% of the total skin biopsies. Pemphigus vulgaris was most common (37.79%). Other VBL included Pemphigus Foliaceous (11.11%), Bullous Pemphigoid and Non–specific Spongiotic Dermatitis (8.89% each). Dermatitis herpetiformis and Dariers disease comprised 4.44%. Less common entities included Bullous SLE, Bullous drug eruption, Epidermolysis bullosa. Conclusion: The dermato–pathologist plays a crucial role in the diagnosis, classification, prognostication and treatment of the individual patient with VBL