Volume : VII, Issue : VI, June - 2017

Hypertonic Saline nebulization in the Viral Bronchiolitis in Infants at Tertiary care center, Bhagalpur

Dr. Rajiv Kumar

Abstract :

 Objective To investigate the use of nebulized 3% hypertonic saline (HS) for treating viral onchiolitis in moderately ill hospitalized infants by a prospective, randomized, double–blinded, controlled, multicenter trial.   Study design A total of 96 infants (mean age, 4.7 months; range, 0.3 to 18 months) admitted to the hospital for treatment of viral onchiolitis were recruited from Jawaharlal Nehru medical college & hospital during onchiolitis seasons (november 2015to marchy 2016). Patients were randomized to receive, in a double–blind fashion, repeated doses of nebulized 3% HS (treatment group) or 0.9% normal saline (NS; control group), in addition to routine therapy ordered by the attending physician. The principal outcome measure was hospital length of stay (LOS).   Results On an intention–to–treat basis, the infants in the HS group had a clinically relevant 26% reduction in LOS to 2.6to 1.9 days, compared with 3.5 to 2.9 days in the NS group (P .05). The treatment was well tolerated, with no adverse effects attributable to the use of HS.   Conclusions The use of nebulized 3% HS is a safe, inexpensive, and effective treatment for infants hospitalized with moderately severe viral onchiolitis. 

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

DR.RAJIV KUMAR, Hypertonic Saline nebulization in the Viral Bronchiolitis in Infants at Tertiary care center, Bhagalpur, INDIAN JOURNAL OF APPLIED RESEARCH : Volume‾7 | Issue‾6 | June‾2017

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