HYPOFRACTIONATION RADIATION TREATMENT IN CARCINOMA BREAST: AN AADHAR HOSPITAL EXPERIENCE

Arun K Aggarwal; Tejpal Sharma; Lovenish Goyal; Harish Sharma; Bharat Bhushan; Anuradha Rani; Anshika Rana

Volume : X, Issue : VII, July - 2020

HYPOFRACTIONATION RADIATION TREATMENT IN CARCINOMA BREAST: AN AADHAR HOSPITAL EXPERIENCE

Arun K Aggarwal, Tejpal Sharma, Lovenish Goyal, Harish Sharma, Bharat Bhushan, Anuradha Rani, Anshika Rana

Abstract :

BACKGROUND: Post–operative radiation treatment to chest wall and draining lymph nodes after surgery in carcinoma east is an established treatment. Start A and Start B trials had suggested that shorter course of radiation can be delivered without compromising efficacy and minimal side effect. MATERIAL, METHODS & RESULT: At AADHAR HOSPITAL a retrospective study of carcinoma east patients presenting to department of radiation from Jan 2017 to Dec 2019. Total of 157 patients were eligible for evaluation and divided in two groups: Group I– standard fractionation (50 Gy/28 F/5.3 wks in MRM patients and a boost of 10Gy/5 F/1 wk for BCS patients, n=90) and Group II hyprofractionation (41 Gy/15F/ 3 Wks to MRM and 7 Gy/ 3F/ 3 days to BCS patients, n=57). All the patients were assessed after radiation, two weeks after radiation, 6 weeks after radiation and at last FU. Radiation toxicity, any local recurrence and any cardiac or respiratory events were noted during this period. There was no difference in the two groups. CONCLUSIONS: Hypofractionation should be the new standard of care and should be offered to most women as it is more convenient and cost–effective. This approach can be both safe and effective and shows even lesser acute radiation toxicity.