Volume : IV, Issue : VI, June - 2014

HYPOVITAMINOSIS D IN TYPE–2 DIABETES MELITUS PATIENTS ; VARIATION WITH AGE, SEX AND SEASON.

Sunusi Usman Maaji, Pranav Kumar Prabhakar

Abstract :

Introduction:Hypovitaminosis D (25[OH] D) with high prevalence in both developed and developing world, has been implicated in the development of diabetes and the metabolic syndrome’ and it has also been shown to play a role in glycaemic control in diabetic patients. The main objective of the present study is to examine the incidence of 25[OH] D insufficiency and deficiency in type–2 DM patient attending Asian Institute of Gastroenterology Hyderabad, and to examine its variation with age, sex, and season. Methods:The parameters of 395 patients with established type–2 DM aged 30years and >50years were categorized by vitamin D status, patients with 25[OH]D levels <20ng/mol as defciency, and 21–29ng/mol as insufficiency and >30ng/mol as sufficiency. Levels of FPG and HbA1C was also recorded. The data obtained were statistically analyzed and presented. Results: Hypovitaminosis D was common, with 66.3%(n 262) of patients affected with deficiency, and 17.5%(n 69) had insufficiency, where as rest 16.2 % (n 64) had sufficiency. A statistical significance p=0.0002was obtained between age and vitamin D status. A positive correlation (r= 0.155) was observed between age and vitamin D status. Negative correlation (r= –0.083) between FPG and vitamin D status was observed. Statistical significance(p=0.015) between season and vitamin D status was observed, also a negative correlation exist between season and vitamin D. There is no significant difference in the distribution of vitamin D deficiency between the two different age groups, but significant difference exist (p=0.0114) between the age group and vitamin D sufficiency. A statistical signifcance (p=0.0001) between male and female with vitamin D deficiency. However no significant difference was observed between male and females who had vitamin d sufficiency (p=0.0561). Conclusions:Hypovitaminosis D encompassing deficiency and insufficiency was common among patients with type–2 DM and varies with age, sex, and season. Being inexpensive vitamin D supplementation might help in attaining better glycemic control and avoidance of early diabetic complications.

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Sunusi Usman Maaji, Pranav Kumar Prabhakar HYPOVITAMINOSIS D IN TYPE-2 DIABETES MELITUS PATIENTS;VARIATION WITH AGE, SEX AND SEASON. Indian Journal of Applied Research, Vol.IV, Issue.VI June 2014


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