Volume : IX, Issue : VI, June - 2019

IDENTIFICATION OF MAJOR DRUG – DRUG INTERACTIONS AT TERITIARY CARE HOSPITAL

V. S. Swathi, B. Lavanya, B. Spandana, M. Yamini

Abstract :

A drug– drug interaction is a clinical event where effect of one drug is altered by other drug when administered concomitantly. Many drug–drug interactions cause late adverse drug reactions which may leads to misinterpretation as new disease condition which further worsens the condition. Drug–drug interactions are can be identified with the help of computer softwares. We conducted the prospective observational study in Teritiary care hospital. The duration of study is from November 2018 to Feuary 2019.We took data from 122 patients during this study period. During 3 months of study, 122 prescriptions are analysed, out of which 52% are males and 70% are females, patients under the age group of 20 to 49 are (n=73) more in number followed by the age group of 50 to79 are (n=41) and the least age group is identified as below 20 (n=8). Most of the people are identified with Cholelithiasis (n=9). Some of them are identified with Acute Appendicitis, followed by Acute Ischemic Stroke, Inguinal Hernia, Acute Pancreatitis and Dengue. , the major drug interactions are identified from different data bases. A total of 22 major drug interactions are identified. Out of these 14 interactions are found in Micromedex, 11 interactions are found in Medscape and 6 are found in Drugs.com. Drug– Drug interactions are common drug related problems which will affect safety and efficacy of the patient but they are generally neglected in health care scenario. Review of prescription using softwares by a pharmacist may decrease chance of drug related problems.

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

IDENTIFICATION OF MAJOR DRUG‾DRUG INTERACTIONS AT TERITIARY CARE HOSPITAL, V.S.Swathi, B.Lavanya, B.Spandana, M.Yamini INDIAN JOURNAL OF APPLIED RESEARCH : Volume-9 | Issue-6 | June-2019

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