Immunohistochemical diagnosis of Breast Cancer cases with prognostic markers: ER, PR & HER2/1

Arup Bhaumik; Shikha Das; Sandeep Roy Sarkar; Payel Chakraborty; Biswajit Chowdhury

Volume : V, Issue : VII, July - 2015

Immunohistochemical diagnosis of Breast Cancer cases with prognostic markers: ER, PR & HER2/1

Arup Bhaumik, Shikha Das, Sandeep Roy Sarkar, Payel Chakraborty, Biswajit Chowdhury

Abstract :

<p>Immunohistochemistry is increasingly used in the assessment of markers for east cancer prognosis. A hospital based study was done to scrutinize the various histopathological facets of east cancer patients along with endocrine therapy. The size of the sample was 55 rangingin age group between 22 to 70 years female patients of Tripura. The most common scoring method used was the H&ndash;score which takes into consideration the staining intensity in conjunction with the percentage of cells staining positively in east carcinoma tissue.They were further divided into estrogen receptor sensitivity, progesterone receptor sensitivity and HER2/neu sensitivity. Results are presented to formulate ultimately a strategy for sustainable integrative model in the management of east cancer. Our study supports IHC classification as a clinical tool,since ER, PR &amp; HER2/neu testing is widely available at a reasonable cost.</p>