Volume : IV, Issue : II, February - 2014

In Vitro Cytotoxicity Activity of Acteoside From Leucas Indica Flowers

A. Vinayagam, P. N. Sudha

Abstract :

The study was aimed to evaluate the in vitro cytotoxicity activity of acteoside isolated from the crude methanolic extract of Leucas indica flowers on the MCF-7 cell line. The acteoside was tested for its inhibitory effect on MCF-7 cell line. The in vitro cytotoxicity of acteoside on MCF-7 cell was evaluated by the MTT assay. Acteoside has significant cytotoxicity effect on MCF-7 cell line in concentration range between 1.0 µg/ml to 250 µg/ml by using MTT assay. IC50 value and R2 value of acteoside on MCF-7 cell and Vero cell were 7.7 and 0.9968, 249.7 and 0.9545 respectively by MTT assay. From the performed assay, acteoside shows greater activity on MCF-7 cell line and little activity on Vero cell line and these values indicates that acteoside from Leucas indica flowers extract shows significant cytotoxicy activity.

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

A. Vinayagam, P. N. Sudha In Vitro Cytotoxicity Activity of Acteoside From Leucas Indica Flowers Indian Journal of Applied Research, Vol.IV, Issue. II


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