Volume : VIII, Issue : IV, April - 2018

Incidence and antibiotic susceptibility pattern of non-fermenting gram negative bacilli: a study in tertiary care hospital

Pramod Kushwaha, Savita B. Jain, K. P. Ranjan, Shashi Gandhi, Gajendra S. Parihar

Abstract :

IntroductionNonfermentative gram–negative bacilli (NFGNB) have emerged as a major cause of health care associated infections.This study was undertaken to know the prevalence of nonfermenters isolated from different clinical samples along with their antibiotic susceptibility pattern.

Material and Methods: Conventional bacteriological methods were used for identification and antibiotic susceptibility testing of nonfermenters. Antibiotic susceptibility testing was performed by methods as recommended by Clinical Laboratory Standard Institute (CLSI).

Results: Out of the 120 isolates, the majority of the non–fermenters were isolated from blood 37(30.83%), followed by pus 32(26.67%), urine 20(16.67%), CSF 16(13.33%), Ascitic fluid 5(4.17%), the rest of the isolates were from other clinical specimens. The most common isolate  wasgenus Pseudomonas (94) and followed bygenusAcinetobacter(26), A.baumanii(22) and  A.lwoffii(04) respectively A high level of antibiotic resistance was recorded for most of the first and second line drugs. Colistin,imipenem,pipercillin –tazobactamandamikacin were  the drugs with maximum activity.

Conclusion:  NFGNB though regarded as contaminants are important bacteria causing wide range of health care associated infections. Irrational use of powerful antibiotics for prolonged periods added to the compromised host conditions might be responsible for multi–drug resistance (MDR). Improved antibiotic usage and infection control measures will be needed to prevent or slow the emergence and spread of multi–drug resistant NFGNB in the healthcare setting.

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Pramod Kushwaha, Savita B. Jain, K. P. Ranjan, Shashi Gandhi, Gajendra S. Parihar, Incidence and antibiotic susceptibility pattern of non-fermenting gram negative bacilli: a study in tertiary care hospital, INDIAN JOURNAL OF APPLIED RESEARCH : Volume-8 | Issue-4 | April-2018

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