INVESTIGATIONAL STUDY TO EVALUATE THE ANTIMICROBIAL ACTIVITY OF FRESH PASTE OF EARTHWORM Octochaetona paliensis.

Rathod Geeta; S.S Hatti; Dr Naresh Rathod

Volume : X, Issue : V, May - 2020

INVESTIGATIONAL STUDY TO EVALUATE THE ANTIMICROBIAL ACTIVITY OF FRESH PASTE OF EARTHWORM Octochaetona paliensis.

Rathod Geeta, S. S Hatti, Dr Naresh Rathod

Abstract :

Earthworms are annelids that are metamerically segmented oligochaetes, In the recent past, the coelomic fluid and paste of few species of these worms have been studied to exhibit antibacterial and antifungal activities. In this study we experiment to understand the antibacterial (bactericidal or bacteriostatic) and antifungal activity of a paste preparation from a species of earthworm named O.paliensis (Octochaetona paliensis) against standard ATCC (American Type Culture Collection) strains of microbes like S.aureus (Staphylococcus aureus), E.faecalis (Enterococcus faecalis, E.coli (Escherichia Coli), P.aeruginosa (Pseudomonas aeruginosa) and C.albicans (Candida albicans). Strain specific antibiotics were used as controls on a petriplate, that was incubated overnight at 37°C for bacteria and 25°C for fungi accordingly and results tabulated. It was concluded that the paste of O.paliensis has definite activity against the standard strains of microbes as compared to the strain specific antibiotics and significant, appreciable activity against the fungal lawn cultures of C. albicans as compared to ketoconazole. Hence the paste of O.paliensis needs to be further studied with different modifications and restructuring of processes and detailed molecular studies are mandated that will clearly explain us the structure of the compound that is exhibiting the antimicrobial activity. This will enable us to exploit such substances for novel discovery of antibacterial and antifungal agents helpful to curb the growing menace of antimicrobial resistance.