Iopamidol in comparison with meglumine sodium  diatrizoate in different concentrations as contrast  media in clinical endodontics � in vivo study

Uday S. Mahale; Mithra N. Hegde; Aditya Shetty; Amit B. Patil; Amit B. Patil

Volume : III, Issue : VI, June - 2013

Iopamidol in comparison with meglumine sodium diatrizoate in different concentrations as contrast media in clinical endodontics � in vivo study

Uday S. Mahale, Mithra N. Hegde, Aditya Shetty, Amit B. Patil, Amit B. Patil

Abstract :

The purpose of this study was to evaluate the clinical efficiency of the newly adopted contrast mediums Iopamidol (IP) in comparison with Meglumine sodium diatrizoate (DZ) at different concentrations in endodontics. Methods : 48 patients with mandibular premolars indicated for root canal therapy were selected. IP and DZ were studied in 30%, 50% and 75% concentrations to form six groups (n=8). The different radiographic contrast mediums were introduced into the pulp space after gaining access. The radiographic images before and after introduction of the contrast mediums were evaluated by three endodontists based on a standardized questionnaire. Inter observer agreement (Kappa) was calculated. Results: The number of root canals observed after introduction of IP75% and DZ50% were increased. DZ50% showed significantly more lateral canals (p = 0.026). IP50% and DZ50% revealed more canals throughout the length as compared to rest of the groups. 50% and 75% concentrations of both the contrast media showed desirable radiopacity. The Odds ratios for intergroup comparison were 20.83 for DZ50% and 14.92 for IP50%, keeping DZ75% as base for the comparison. Conclusion: The newer contrast medium IP showed results comparable with DZ. 50% concentration of both the contrast media showed desirable flow and radiopacity. Hence Iopamidol can be used as contrast medium in endodontics.