Volume : IX, Issue : I, January - 2019

Laparoscopic Tubal Ligation - Comparison of different drugs for sedation

Dr. Kiran Sharma, Dr. Kreety Garg

Abstract :

A study was conducted to compare the sedation given by injection pentazocine with promethazine , inj. ketamine with midazolam and inj. propofol infusion in patients undergoing day care laparoscopic tubal ligation under local anesthesia. 90 patients belonging to ASA I and II, undergoing laparoscopic tubal ligation under local anesthesia were randomly allocated into three equal groups. Group A (n= 30) received inj. pentazocine (fortwin ) 0.5 mg /kg with inj .promethazine (phenargan) 0.5 mg/kg intravenously, group B (n =30) received inj. midazolam 0.05mg/kg with inj. ketamine 0.5mg /kg and group C (n =30) received inj. propofol bolus 0.5mg kg followed by infusion at 50 µg /kg /min. All the patients received local anesthesia with 10ml of 2% xylocaine with adrenaline (1:2,00,000) at the site of incision. Patients were assessed for level of sedation, pain and discomfort during the procedure. Rescue analgesia was given with inj. fentanyl 1 µg /kg bolus intravenously. Results were analysed statistically using MANOVA (Multivariate Analysis of Variance). P value < 0.05 was considered significant. Result: Pain and discomfort was observed in 33 % patients in Group A, 6.6% in Group B and 10 % in Group C. Time to recovery and discharge was comparable in all the three groups. Conclusion: Minimal pain and discomfort was observed in patients who had received inj. ketamine with midazolam and in patients who received inj .Propofol infusion.

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

LAPAROSCOPIC TUBAL LIGATION - COMPARISON OF DIFFERENT DRUGS FOR SEDATION, Dr. Kiran Sharma, Dr. Kreety Garg INDIAN JOURNAL OF APPLIED RESEARCH : Volume-9 | Issue-1 | January-2019

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