Volume : X, Issue : VI, June - 2020

Left Ventricular Hypertrophy and Dysfunction in patients of Chronic Kidney Disease

Kamlesh Taori, Seema Seth, Darshan Mehra

Abstract :

Introduction: CKD prevalence is still growing worldwide confers a higher risk of coronary artery disease, chronic heart failure and/or death independent of conventional cardiovascular risk factors. This study was undertaken to study about left ventricular hypertrophy and dysfunction in patients of CKD, to aid the future efforts that should concentrate on calculation of these well–known contributing factors & to make strategies to prevent cardiovascular problems in CKD patients. Aim: To study about left ventricular hypertrophy and dysfunction in patients of Chronic Kidney Diseases. Material and Method: This cross sectional, hospital based study was performed on 50 CKD patients admitted in the Department of General Medicine at Rohilkhand Medical College, Bareilly, UP . Detailed clinical examination and routine investigations including 2D–ECHO were done. The data was collected, computed and was statistically analyzed. Results: 50 cases were included in our study with the mean age 42.1±16.01 years. The chief complaint was oliguria followed by puffiness of face, weakness, nausea, eathlessness and palpitation. The majority of patients were having severe (stage 5) CKD with 68.0% patients followed by stage 4 CKD with 22.0% patients and the least were of stage 3 CKD with 10.0% patients. Out of 50 patients 28 (56.0%) patients had left ventricular–hypertrophy on echocardiography while 26 (52.0%) on ECG and it was found that LVH showed a progressive rise with increase in severity of renal failure. Hemoglobin was significantly lower in the severe CKD group when compared to the moderate and mild categories. 15 hypertensive patients had LVH while 10 hypertensive patients had no LVH. There was no statistically major difference seen in the age, blood pressure and serum calcium between the three categories of CKD patients while urea (mg/dl), serum bilirubin direct (mg/dl), serum creatinine (mg/dl), serum sodium (m mol/L) and serum phosphate (mg/dl) were statistically significant (p<0.05) . 15 diabetic patients had LVH while 12 diabetic patients had no LVH. ECHO parameters like IVS and PWd could be used independently as predictors of LVH. Conclusions: LVH has a high prevalence in CKD and is a typical feature of CKD–related cardiopathy. The LVH and LV dysfunction progressively increases with increasing severity of chronic kidney disease. Adequate control of blood pressure and anemia is important to forestall the development and progression of CKD, related LVH and other end organ damage. Echocardiography provides a simple, non–invasive investigation that can identify even asymptomatic patients at an earlier stage of CKD.

Keywords :

Article: Download PDF    DOI : 10.36106/ijar  

Cite This Article:

LEFT VENTRICULAR HYPERTROPHY AND DYSFUNCTION IN PATIENTS OF CHRONIC KIDNEY DISEASE, Kamlesh Taori, Seema Seth, Darshan Mehra INDIAN JOURNAL OF APPLIED RESEARCH : Volume-10 | Issue-6 | June-2020

Number of Downloads : 171

References :