Volume : VI, Issue : IX, September - 2016

Low level of activated protein C and protein S in patients with Systemic Lupus Erythematosus are associated with thrombosis.

Vijayta Singh, Vivek Kumar Singh, Rashmi Kushwaha

Abstract :

 Thrombosis is a well–known clinical entity in patients with Systemic Lupus Erythematosus (SLE), and it is multifactorial. In this study we analyze activated protein C and protein S levels in a patient of SLE as a risk factor for thrombosis. A prospective case–control study was performed in a pathology department KGMU, Lucknow in year 2014–2015. 40 diagnosed patients with SLE and 40 control of same age and sex were included in this study. Plasma protein C and protein S activity were studied in above patients. After analysis, thrombotic episodes were seen in 15% of SLE patients. Reduced plasma protein C and protein S level were found to be a risk factor for thrombosis and hence it may be advisable to suggest screening tests for thrombotic risk factors at the time of SLE diagnosis to prevent life threatening thrombotic complications.

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Vijayta Singh, Vivek kumar singh, Rashmi Kushwaha Low level of activated protein C and protein S in patients with Systemic Lupus Erythematosus are associated with thrombosis. Indian Journal of Applied Research,Volume : 6 | Issue : 9 | September 2016

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