MEMBRANE STABILIZING ACTIVITY OF ARUMUGA CHENDOORAM ON MEMBRANE BOUND ENZYMES IN EXPERIMENTAL RATS

R. Albert Santhanaraj Deepak; V. Elango

Volume : VII, Issue : VII, July - 2017

MEMBRANE STABILIZING ACTIVITY OF ARUMUGA CHENDOORAM ON MEMBRANE BOUND ENZYMES IN EXPERIMENTAL RATS

R. Albert Santhanaraj Deepak, V. Elango

Abstract :

Memane fluidity plays a major role to maintained the mitochondrial activity and its evidences through the functional loss of memane bound enzyme ATPases such as Na⁺/K⁺ ATPase, Ca²⁺ ATPase and Mg²⁺ ATPase Supplementation of Arumuga chendooram to methimazole treatedrats restored the decreased activity of Na⁺/K⁺, Ca²⁺ and Mg²⁺ ATPases in thyroid of methimazole treated rats were observed in the present study. The results of the present study indicate that the protective role of Arumuga chendooram in methimazole treatedinduced oxidative stress in rats may be related to counteraction of free radicals. These findings suggest that the memane stabilizing activity of Arumuga chendooram may indeed play a pivotal role in attenuating free radical damage on thyroid memane.