METAPLASTIC BREAST CARCINOMA WITH UNDIFFERENTIATED SPINDLE CELL SARCOMA AND SQUAMOUS METAPLASIA:A Case Report.

Dr. Muktanjalee Deka; Dr. Tulika Thakuria

Volume : IX, Issue : VI, June - 2019

METAPLASTIC BREAST CARCINOMA WITH UNDIFFERENTIATED SPINDLE CELL SARCOMA AND SQUAMOUS METAPLASIA:A Case Report.

Dr. Muktanjalee Deka, Dr. Tulika Thakuria

Abstract :

Introduction: Metaplastic east carcinoma(MBC)s are heterogeneous group of neoplasms accounting for 0.2–5.0% of all east carcinomas. Incidence is <1% of all invasive east carcinoma. Considering only the tumours with mesenchymal metaplasia, MBC accounts for approximately 1% of invasive east carcinoma. Case Report: We report a case of 30–year–old female presented with a gradually progressive palpable mass in the right east for 6 months. FNAC of the mass showed loosely cohesive clusters, sheets and singly dispersed hyperchromatic, pleomorphic epithelial cells and spindle cells. Histopathological examination of the tumour showed an admixture of infiltrating ductal carcinoma with spindle cell sarcoma and focal squamous metaplasia. Based on these features the diagnosis of Metaplastic east carcinoma with undifferentiated spindle cell sarcoma and squamous metaplasia was made. The diagnosis was confirmed with immunohistochemistry. Conclusion: MBCs are rare primary east malignancy, aggressive, chemoresistant and carry a poor prognosis