(Metastatic) Multifocal meningeal melanocytoma of anterior cranial fossa: “a unique case report “and review of literature

Sudhakar.K; Amrutha G; Srinivas BH; Shivakumar.S

Volume : VI, Issue : III, March - 2016

(Metastatic) Multifocal meningeal melanocytoma of anterior cranial fossa: “a unique case report “and review of literature

Sudhakar. K, Amrutha G, Srinivas Bh, Shivakumar. S

Abstract :

 Melanocytomas are borderline tumors between Nevus and melanoma (1,2,4).Posterior fossa, base of skull and spinal cord are most frequently reported sites in the nervous system, but these tumors are very rare in the anterior cranial fossa, but very few cases of meningeal Melanocytomas reported in the literature (2). Metastases is extremely rare in Melanocytomas, however pigmented epethelioid Melanocytomas are known to produce nodal metastases(3).Yourself Ali et al(4) Poalo Merciadri(5) published two different cases of Multifocal Meningeal Melanocytomas from spine, spread to CNS through CSF.The aim of this report is, this is the first case, best of our knowledge, reporting metastases in Melanocytomas. A 47 years female patient, who is a house wife presented with complaints of head ache, vomitings and weakness of right side of the body. She was evaluated in the neurosurgery department, found to have anterior cranial mass by contrast enhanced CT, and underwent total excision. Post–operative histopathology suggested melanocytoma. Post–operative period went uneventful, Patient has improved symptomatically. Post–operative MRI showed multiple sites of ain metastases. We found retrospectively Nevus over anterior chest wall, which has been sent for excision biopsy, however Nevus not shown any features of melanoma by pathological examination. Conclusion: Melanocytomas of anterior cranial fossa are very rare. Although they are benign (1, 2, 4) locally aggressive, although nodal metastases is reported from PEM in few case reports, metastases is extremely rare.