Volume : V, Issue : XII, December - 2015

Microbiological profile of Ventilator Associated Pneumonia cases in a tertiary care hospital, in Dehradun India

Noopur Goel, Sulekha Nautiyal, Shalabh Jauhari, Vinay Rai

Abstract :

Background Ventilator–associated pneumonia (VAP) is a leading cause of death in hospitalized patients, but there has been no systematic analysis of the incidence, microbiology, and outcome of VAP in developing countries. Methods The aim of the study is to critically review the incidence and outcome, identify various risk factors and conclude specific measures that should be undertaken to prevent VAP. We studied 40 patients randomly, kept on ventilator support for more than 48 hours. After excluding those who developed pneumonia within 48 hours, VAP was diagnosed when a clinical pulmonary infection score of ≥six was obtained. Endotracheal aspirates (ETA) were collected from patients with suspected VAP. Findings In this study, incidence of VAP was found to be 70% of which 50% were polymicrobial. Multidrug resistant bacteria, mainly Acinetobacter baumannii, and Pseudomonas aeruginosa were the most common pathogens isolated. While Klebsiella pneumoniae has emerged as the as the most resistant strain showing sensitivity only to polymyxin B of the drugs tested. Interpretation The observations of this study indicate that occurrence of VAP in patients on mechanical ventilation with no other predisposing factors is still a major concern in developing countries. Repeated monitoring of the endotracheal aspirates for early diagnosis, and its antibiogram will guide for an approach to targeted treatment. Thus assist in tackling the serious problem of MDR faced in ICU environment.

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Noopur Goel, Sulekha Nautiyal, Shalabh Jauhari, Vinay Rai Microbiological Profile of Ventilator Associated Pneumonia Cases in a Tertiary Care Hospital, in Dehradun India Indian Journal of Applied Research, Vol.5, Issue : 12 December 2015

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