Monitoring of Community-Acquired Pneumonia using High Sensitivity C - reactive protein (hs CRP) as a Marker

Dr Jainendra Kumar; Dr Akhilesh Singh; Dr. Anant Narayan Sinha

Volume : VIII, Issue : IV, April - 2018

Monitoring of Community-Acquired Pneumonia using High Sensitivity C - reactive protein (hs CRP) as a Marker

Dr Jainendra Kumar, Dr Akhilesh Singh, Dr. Anant Narayan Sinha

Abstract :

Pneumonia is a leading cause of death affecting all age group especially young adults, old and chronically ill individuals. C–reactive protein is an acute phase protein which is synthesized in liver and its level rise in response to inflammation. Interleukins (IL) –6 released by macrophages and adipocytes triggers the synthesis of C–reactive protein in liver although tumor necrosis factor (TNF)–alpha, IL–1, and other cytokines are thought to be involved in the release of C–reactive protein. Evidence of a relationship with severity is still unclear, with some studies showing no correlation of TNF–alpha, IL–6, and soluble interleukin–2 receptor (IL–2R) do with severity. In present study we have determined a correlation between estimation of hsCRP levels and and outcome of patients with pneumonia.