Volume : VI, Issue : VI, June - 2016

Myeloperoxidase variants (at SNP �463 G/A) and the risk of coronary artery disease (CAD): a case control study

Dr. G. Rajashekar Reddy, Dr. K. Laxman Rao, Dr. Vinod K Unni, Dr. Parvaiz Kadloor, Nausheen Fatima, Dr. Parveen, Dr. M. Ishaq

Abstract :

 The aim of the study was to evaluate the role of single nucleotide polymorphism (SNP) at –463 G/A position by PCR in predisposition to coronary artery disease. A total of 69 CAD patients to an equal number of healthy subjects were included in the study. The frequency of AA genotype in patients was 1.44% compared to 5.79% in healthy controls. Odd ratio analysis revealed a OR=0.24 indicating that persons with AA genotypes have about 76% reduced risk of CAD.

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Dr.G. Rajashekar Reddy, Dr.K. Laxman Rao, Dr. Vinod K unni, Dr. Parvaiz Kadloor, Nausheen Fatima, Dr. Parveen, Dr. M.Ishaq Myeloperoxidase variants (at SNP �463 G/A) and the risk of coronary artery disease (CAD): a case control study Indian Journal of Applied Research, Vol.6, Issue : 6 JUNE 2016


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