Neurocognitive functioning in patients with temporal lobe epilepsy � A controlled study

Dr. Pradhyuman Chaudhary; Dr. Girish Banwari; Dr. Nimesh Parikh; Dr. Hitendra Gandhi

Volume : VI, Issue : VIII, August - 2016

Neurocognitive functioning in patients with temporal lobe epilepsy � A controlled study

Dr. Pradhyuman Chaudhary, Dr. Girish Banwari, Dr. Nimesh Parikh, Dr. Hitendra Gandhi

Abstract :

Objective: The study aim to the assess the neurocognitive functioning of patients with temporal lobe epilepsy with either right or left side mesial temporal sclerosis. Methods and Material: Patients diagnosed with temporal lobe epilepsy (confirmed on video EEG) and evident mesial temporal sclerosis (right or left) on MRI Brain was subjected to neurocognitive evaluation on two instruments– PGI Battery of Brain Dysfunction (BBD) and Addenooke’s Cognitive Examination – ACE–R, Hindi version 2006 for literate subjects and 2010 for illiterate subjects. Areas of cognitive functioning assessed would include memory (verbal and visual), language, intelligence (verbal and performance), visuo–spatial ability, and attention and concentration. Age, gender, education and handedness matched healthy controls with no present/past/family history of epilepsy were subjected to similar neurocognitive assessment for comparison. Results: Remote & Recent Memory, Verbal Memory and visual Memory impairment on PGI battery for Brain Dysfunction for mesial temporal epileptics patients as compare to control. Memory, Fluency, language, visuo – spatial impairment on Addenooke’s Cognitive Examination Hindi Version 2006 (for literate) and 2010 (for illiterate) for mesial temporal epileptics patients as compare to control